DIFFERENTIAL ACTIVATION OF NEUROPEPTIDE FF RECEPTORS BY GONADOTROPIN-INHIBITORY HORMONE PEPTIDES IN THE EUROPEAN SEA BASS

Differential activation of neuropeptide FF receptors by gonadotropin-inhibitory hormone peptides in the European sea bass

Neuropeptide FF (NPFF) and gonadotropin-inhibitory hormone (GnIH) are thought to be paralogous, and a recent study has revealed that both NPFF and GnIH peptides can activate the GnIH receptor (GnIHR, also called NPFFR1) in the European sea bass (Dicentrarchus labrax).However, whether GnIH can bind to the NPFF receptor (NPFFR2) is still yet unknown

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Schizophrenia endothelial cells exhibit higher permeability and altered angiogenesis patterns in patient-derived organoids

Abstract Schizophrenia (SCZ) is a complex neurodevelopmental disorder characterized by the manifestation of psychiatric symptoms in early adulthood.While many research avenues into the origins of SCZ during brain development have been explored, the contribution of endothelial/vascular dysfunction to the disease remains largely elusive.To model the

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Placement of social bonds through crowdfunding: Global trends and prospects for implementation in domestic practice

The article considers the possibility of using additional sources of financing in the construction and operation of social infrastructure facilities.We are talking about the use of social bonds.The idea belongs to the International Capital Markets Association (ICMA), where the issue of social bonds is designed to solve specific problems of society,

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Complete and sustained resolution of calcinosis universalis in a juvenile dermatomyositis case with mycophenolate mofetil

Juvenile dermatomyositis (JDM) is a rare, multisystemic, idiopathic vasculopathy mainly affecting the muscles and the skin.Gastrointestinal system, lungs, joints and heart may also be involved.Characteristic skin findings are heliotrope rash and Gottron papules but extensive skin involvement as large necrotic lesions are rarely reported.Calcinosis

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